Breast cancer in young women: Pathologic features and molecular phenotype

Breast cancer in young women: Pathologic features and molecular phenotype
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DOI:
10.1016/j.breast.2016.07.007
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发表时间:
2016-10-01
期刊:
影响因子:
3.9
通讯作者:
Lambaudie, Eric
Lambaudie, Eric
中科院分区:
医学2区
文献类型:
--
作者:
Sabiani, Laura;Houvenaeghel, Gilles;Lambaudie, Eric

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目的:对年轻女性乳腺癌的预后存在争议。我们的目标是描述临床病理和预后特征,以改善辅助治疗指征。方法:我们进行了一项包括15家法国医院的多中心回顾性研究。结果:共纳入5815例患者,其中35~40岁占15.6%,35岁以下占8.7%。在94%的病例中,患者体内有明显的肿块。
Purpose: Controversy exists about the prognosis of breast cancer in young women. Our objective was to describe clinicopathological and prognostic features to improve adjuvant treatment indications.Methods: We conducted a retrospective multi centre study including fifteen French hospitals. Disease free survival's data, clinical and pathological criteria were collected.Results: 5815 patients were included, 15.6% of them where between 35 and 40 years old and 8.7% below 35. In 94% of the cases, a palpable masse was found in patients