Macrocyclic nonviral vectors: High cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene
Macrocyclic nonviral vectors: High cell transfection efficiency and low toxicity in a lower rim guanidinium calix[4]arene
复制标题
DOI：
10.1021/ol801326d
复制
发表时间：
2008-09-18
期刊：
影响因子：
5.2
通讯作者：
Ungaro, Rocco
中科院分区：
文献类型：
--
作者：
Bagnacani, Valentina;Sansone, Francesco;Ungaro, Rocco
通过在杯[4]芳烃的下缘连接胍基团，得到了一种新型的多价阳离子脂类，其中一种在细胞转染中表现出高效和低毒。
New multivalent cationic lipids, one of them showing high efficiency and low toxicity in cell transfection, have been obtained by attaching guanidinium groups at the lower rim of calix[4]arenes.