The HLA Dictionary 2004: a summary of HLA-A, -B, -C,-DRB1/3/4/5 and -DQB1 alleles and their association with serologically defined HLAA -B, -C, -DR and -DQ antigens
The HLA Dictionary 2004: a summary of HLA-A, -B, -C,-DRB1/3/4/5 and -DQB1 alleles and their association with serologically defined HLAA -B, -C, -DR and -DQ antigens
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DOI：
10.1111/j.1744-313x.2005.00497.x
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发表时间：
2005-02-01
影响因子：
2.2
通讯作者：
Maiers, M
中科院分区：
文献类型：
--
作者：
Schreuder, GMT;Hurley, CK;Maiers, M
本文介绍了人类白细胞抗原-A、-B、-C、-DRB1、-DRB3、-DRB4、-DRB5和-DQB1等位基因的血清学等价物。这本词典是2001年出版的词典的更新版。这些数据汇总了世界卫生组织人类白细胞抗原系统因子命名委员会、国际细胞交换(UCLA)、国家骨髓捐赠者计划(NMDP)、最近的出版物和个别实验室获得的等价物。词典的这一最新更新通过纳入第13届国际组织相容性研讨会期间进行的研究和神经网络分析的结果而得到加强。作为推荐的血清学等效物的数据摘要以专家指定的类型呈现。这些表格包括等位基因的注释，这些等位基因是或可能被表达为具有不同于公认的人类白细胞抗原特异性的血清学反应模式的抗原。所提供的等价物将有助于指导搜索无关的造血干细胞捐赠者，其中患者和/或潜在捐赠者通过血清学或基于DNA的方法进行分型。血清学DNA等值词典还将帮助器官移植方案的分型和配对程序，这些方案的潜在捐赠者和接受者的等待名单包括血清学和DNA分型的混合。含有人类白细胞抗原等效物的表格和用于提交识别不良等位基因产品的血清学反应模式的调查表将通过WMDA网页(www.Worldmarrow.org)提供，在不久的将来，还将以可在IMGT/人类白细胞抗原数据库上搜索的形式提供。
This report presents serological equivalents of HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5 and -DQB1 alleles. The dictionary is an update of that published in 2001. The data summarize equivalents obtained by the World Health Organization Nomenclature Committee for Factors of the HLA System, the International Cell Exchange (UCLA), the National Marrow Donor Program (NMDP), recent publications and individual laboratories. This latest update of the dictionary is enhanced by the inclusion of results from studies performed during the 13th International Histocompatibility Workshop and from neural network analyses. A summary of the data as recommended serological equivalents is presented as expert assigned types. The tables include remarks for alleles, which are or may be expressed as antigens with serological reaction patterns that differ from the well-established HLA specificities. The equivalents provided will be useful in guiding searches for unrelated haematopoietic stem cell donors in which patients and/or potential donors are typed by either serology or DNA-based methods. The serological DNA equivalent dictionary will also aid in typing and matching procedures for organ transplant programmes whose waiting lists of potential donors and recipients comprise mixtures of serological and DNA-based typings. The tables with HLA equivalents and a questionnaire for submission of serological reaction patterns for poorly identified allelic products will be made available through the WMDA web page (www.worldmarrow.org) and, in the near future, also in a searchable form on the IMGT/HLA database.