Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy
Transient Splenial Lesion of the Corpus Callosum in H1N1 Influenza Virus-Associated Encephalitis/Encephalopathy
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DOI：
10.2169/internalmedicine.50.4147
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发表时间：
2011-01-01
影响因子：
1.2
通讯作者：
Mutoh, Tatsuro
中科院分区：
文献类型：
--
作者：
Ito, Shinji;Shima, Sayuri;Mutoh, Tatsuro
一名26岁男子因H1N1流感病毒相关脑炎/脑病引起的高烧、嗜睡、记忆障碍和定向障碍而入院。甲强的松龙脉冲治疗后症状迅速好转。脑磁共振成像（MRI）弥散加权图像显示胼胝体中央脾有一个大的瞬时高信号病变。在临床轻度季节性流感相关脑炎/脑病病例中，这一MRI发现与临床完全康复相结合，也可作为诊断新型流感（H1N1流感病毒感染并发脑炎/脑病）的有用线索。
A 26-year-old man was admitted to our hospital because of high fever, drowsiness, memory disturbance, and disorientation due to H1N1 influenza virus-associated encephalitis/encephalopathy. All of his symptoms rapidly improved following methylprednisolone pulse therapy. The diffusion-weighted image of brain magnetic resonance imaging (MRI) revealed a large transient hyperintense signal lesion on the central splenium of the corpus callosum. This MRI finding in conjunction with a complete clinical recovery has been previously observed in cases of clinically mild seasonal influenza-associated encephalitis/encephalopathy, and can be also a useful clue for the diagnosis of new type of influenza, H1N1 influenza virus infection complicated by encephalitis/encephalopathy.