Rapid Antigen Testing for Trichomoniasis in an Emergency Department.
Rapid Antigen Testing for Trichomoniasis in an Emergency Department.
复制标题
急诊科中毛瘤病的快速抗原测试。
DOI：
10.1542/peds.2015-2072
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发表时间：
2016-06
期刊：
影响因子：
8
通讯作者：
Widdice LE
中科院分区：
文献类型：
--
作者：
Postenrieder NR;Reed JL;Hesse E;Kahn JA;Ding L;Gaydos CA;Rompalo A;Widdice LE
Trichomoniasis is a prevalent cause of vaginitis among adolescents that increases the risk of acquiring other sexually transmitted infections and is associated with negative pregnancy outcomes. Therefore, treatment of trichomoniasis is essential for improving sexual and reproductive health outcomes. A timely, sensitive diagnostic test for T vaginalis may increase accuracy of clinician's treatment decisions resulting in more infected women receiving treatment and fewer uninfected women receiving treatment. Retrospective observational study of electronic medical records during 2 time periods: before (pre-POC) and after (post-POC) implementation of the rapid antigen test. Records were collected from women aged 14-20 years who received a T vaginalis test in the emergency department during either study period. The main outcome measures were the rates of accurate treatment, inaccurate treatment, and missed treatment of trichomoniasis in each study period. Overall rates of accurate treatment increased from 78.7% pre-POC to 87.7% post-POC (P=0.02). Specifically, rates of not treating uninfected women increased from 61.4% pre-POC to 70.4% post-POC (P=0.06) and rates of treating infected women were the same pre-POC (17.3) and post-POC (17.3, P=0.99). Rates of inaccurate treatment decreased from 23.1% pre-POC to 13.1% post-POC (P=.02). Changes in rates of missed treatment (14.0% pre-POC and 8.8% post-POC, P=0.73) were not statistically significant. Point-of-care testing can impact clinical care by decreasing use of antibiotics in uninfected women. The results of this study provide support for the use of a T vaginalis rapid antigen POC test for adolescents presenting to the emergency department.
