Severe fever with thrombocytopenia syndrome in China.
Severe fever with thrombocytopenia syndrome in China.
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DOI：
10.1016/s1473-3099(18)30569-3
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发表时间：
2018-11
期刊：
影响因子：
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通讯作者：
M. Yan;W. Niu
中科院分区：
文献类型：
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作者：
M. Yan;W. Niu
通信www.我的天使com/infection 2018年11月18日1181综合征（SFTS）和中国的相关死亡率。作者报告了实验室诊断的SFTS流行病学特征的变化，以及与SFTS相关的高病死率，1强调了中国迫切需要加强对该疾病的监测计划。虽然我们同意这篇文章的结论，但我们对结果及其解释表示关切。首先，从信阳的单中心研究中得出的结果对整个中国的普遍性可能是有限的，尽管该综合征起源于信阳，SFTS的发病率仍然流行。1因此，将调查结果从地方一级转化为国家一级可能为时过早。其次，为了便于预测SHTS相关的死亡率，作者创建了一个基于年龄，神经系统症状和四个实验室指标的临床评分模型。使用相同的权重（1至3）对变量进行评分，这可能无法准确反映SFTS的预后。我们建议使用几种广泛采用的评分系统，如FractionalStudy风险评分，2基于生存率的评分系统，3和标准化Z评分系统。4需要一个更准确的评分系统，可以更好地评估SHTS相关的死亡率。
Correspondence www. thelancet. com/infection Vol 18 November 2018 1181 syndrome (SFTS) and associated mortality in China. The authors report a changing epidemiological profile of SFTS diagnosed in laboratories, and a high SFTS-associated case fatality rate, 1 underscoring the urgent need for enhanced surveillance programmes for this disease in China. Although we agree with the conclusions of this Article, we have concerns about the results and their interpretation. First, the generalisability of the findings derived from a single centre study in Xinyang to the whole of China might be limited, although the syndrome originated in Xinyang, where the incidence of SFTS remains epidemic. 1 Thus, translation of findings from the local level to the national level might be premature. Second, to facilitate the prediction of SFTS-associated mortality, the authors created a clinical scoring model based on age, neurological symptoms, and four laboratory indicators. Identical weights (1 to 3) were used to score the variables, which might not accurately reflect SFTS prognosis. We recommend the use of several widely adopted scoring systems, such as the Framingham Study risk score, 2 survival-rate-based scoring system, 3 and the standardised Z-score system. 4 A more accurate scoring system that can better assess SFTS-associated mortality is needed.