Physiological significance of cyclic changes in room temperature around dusk and dawn for circadian rhythms of core and skin temperature, urinary 6-hydroxymelatonin sulfate, and waking sensation just after rising
Physiological significance of cyclic changes in room temperature around dusk and dawn for circadian rhythms of core and skin temperature, urinary 6-hydroxymelatonin sulfate, and waking sensation just after rising
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DOI：
10.2114/jpa2.26.429
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发表时间：
2007-06-01
影响因子：
3.1
通讯作者：
Oishi, Tadashi
中科院分区：
文献类型：
--
作者：
Kondo, Masayuki;Tokura, Hiromi;Oishi, Tadashi
本研究调查了黄昏和黎明前后的室温(T-a)周期是否会影响人类夜间睡眠时直肠温度(T-core)的昼夜节律、尿6-羟基黑素硫酸盐以及对睡眠的主观评估。六名女学生和两名男学生作为参与者。建立了循环和常量两种不同的T-a条件。给受试者提供了两种室温：循环T-a(1800-2200小时从27摄氏度逐渐下降到24摄氏度，0300-0700小时从24摄氏度逐渐上升到27摄氏度)和T-a(24小时27摄氏度)。在周期T-a时，T-core节律的昼夜节律和恒定T-a值显著提前，而T-core在2300-0200h显著降低，0600-1000h显著升高，夜间尿液中6-羟色胺硫酸盐浓度在夜间显著升高。周期T-a组起床后的觉醒感觉明显好于对照组。(四肢皮肤温度-T-a)循环T-a显著较高，特别是在傍晚和夜间。我们的结果表明，在晚上和清晨逐渐改变室内温度对促进睡眠和新鲜觉醒很重要。人类似乎已经进化成在黄昏和黎明前后，在周期性T的影响下有更深的睡眠。
The present study investigated whether room temperature (T-a) cycles around dusk and dawn could influence the circadian rhythm of rectal temperature (T-core), urinary 6-hydroxymelatonin sulfate during nocturnal sleep, and subjective assessments of sleep in humans. Six female and two male students served as participants. Two different T-a conditions, cyclic and constant, were established. Two kinds of room temperature were provided to subjects: cyclic T-a, (gradual decrease from 27 degrees C to 24 degrees C between 1800 and 2200h and gradual increase from 24 degrees C to 27 degrees C between 0300 and 0700 h), T-a (27 degrees C over 24h). At cyclic T-a, the circadian and constant T-a nadir of T-core rhythm was significantly advancea while T-core was significantly lower from 2300 to 0200h and significantly higher from 0600 to 1000 h. The nocturnal concentration of 6-hydroxymelatonin sulfate in the urine during sleep was significantly higher during cyclic T-a. Waking sensation just after rising was significantly better with cyclic T-a. (Skin temperatures in the extremities - T-a) were significantly higher with cyclic T-a especially during the evening and night. Our results suggest that gradual change of room temperature in the evening and early morning is important in terms of sleep promotion and fresh awakening. It seems probable that mankind has been evolved to have deeper sleep under the influence of cyclic T. around dusk and dawn.