A Prospective Study of Cutaneous Findings in Newborns in the United States: Correlation with Race, Ethnicity, and Gestational Status Using Updated Classification and Nomenclature
A Prospective Study of Cutaneous Findings in Newborns in the United States: Correlation with Race, Ethnicity, and Gestational Status Using Updated Classification and Nomenclature
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DOI：
10.1016/j.jpeds.2012.02.052
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发表时间：
2012-08-01
影响因子：
5.1
通讯作者：
Friedlander, Sheila Fallon
中科院分区：
文献类型：
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作者：
Kanada, Kimberly Natee;Merin, Melissa Reyes;Friedlander, Sheila Fallon
目的提供基于种族、早产和身体部位的血管性、色素和其他常见先天性皮肤表现的发病率数据；将这些结果与先前发表的前瞻性研究进行比较；并为儿科医生定义最新的命名、分类、临床病程和预后因素，以促进对良性与更令人担忧的胎记的更好理解。这项前瞻性研究在加州圣地亚哥招募了594名婴儿。儿童皮肤科医生在出生后48小时内进行皮肤检查，随后通过电话进行纵向接触，如果父母报告有任何新的病变，则重复评估。发病率按种族和早产状况计算。结果血管病变以单纯痣型为主（83%），其次为婴幼儿血管瘤（4.5%），其次为毛细血管畸形（0.3%），最后为快速渐开式先天性血管瘤（0.3%）。出生时出现的色素病变包括皮肤黑色素细胞增多症（20%）、先天性黑色素细胞痣（2.4%）和咖啡黑斑（2%）。其他常见的皮肤表现为新生儿毒性红斑（7%）、粟疹（8%）和皮脂腺增生（42.6%）。结论：这项先天性皮肤病变的研究，使用当前的命名法和儿科皮肤病变专家获得的数据，提供了关于种族和民族在胎记发生率中的作用的数据，并提供了关于婴儿血管瘤患病率的有效数据。[J] .中华儿科杂志（英文版）；2012;31(5):591 - 591。
Objective To provide incidence data based on ethnicity, prematurity, and body site for vascular, pigmented, and other common congenital cutaneous findings; to compare these results with previously published prospective studies; and to define updated nomenclature, classification, clinical course, and prognostic factors for the pediatric practitioner to promote a better understanding of benign versus more worrisome birthmarks.Study design This prospective study enrolled 594 infants in San Diego, California. Cutaneous examination was performed by pediatric dermatologists in the first 48 hours of life, with subsequent longitudinal contact via telephone, and repeat evaluations if any new lesions were reported by parents. Incidence rates were calculated by ethnicity and prematurity status.Results The most common vascular lesion was nevus simplex (83%), followed by infantile hemangioma (4.5% by age 3 months), capillary malformation (0.3%), and rapidly involuting congenital hemangioma (0.3%). Pigmented lesions seen at birth included dermal melanocytosis (20%), congenital melanocytic nevi (2.4%), and cafe au lait macules (2%). Other common skin findings were erythema toxicum neonatorum (7%), milia (8%), and sebaceous gland hyperplasia (42.6%).Conclusion This study of congenital cutaneous lesions, using current nomenclature and data acquired by pediatric cutaneous lesion experts, provides data regarding the role of race and ethnicity in the incidence of birthmarks, and provides valid data on the prevalence of infantile hemangioma. (J Pediatr 2012;161:240-5).