The health implications of low hemoglobin deferral in infrequent blood donors.
The health implications of low hemoglobin deferral in infrequent blood donors.
复制标题
低血红蛋白延迟对不频繁献血者的健康影响。
DOI：
10.1111/trf.12801
复制
发表时间：
2015
期刊：
影响因子：
2.9
通讯作者：
Mast,AlanE
中科院分区：
文献类型：
--
作者：
Annen,Kyle;Delaney,Meghan;Leitch,Dave;Mast,AlanE
背景因低血红蛋白（Hb）而推迟献血的不常献血者贫血的原因尚不清楚。我们试图通过对威斯康星州血液中心和普吉特湾血液中心这两个机构的不频繁的、非自愿的推迟献血者的调查来评估这一点。（≤12.5 g/dL），在推迟前一年内献血不超过1次，结果总应答率为34%（380例）。在受访者中，有141人曾就他们的低血红蛋白寻求医疗建议。其中，90人被证实有贫血和13个严重的疾病，需要医疗干预，包括套细胞淋巴瘤，多发性骨髓瘤，消化道bleeding.ConclusionsA小，但有关数量很少的献血者推迟低血红蛋白有一个潜在的疾病，是严重的，将受益于医疗照顾。对于因低血红蛋白而推迟献血的严重基础疾病风险较高的献血者，应提供有针对性的教育信息，建议他们寻求额外的医疗护理。
BackgroundThe causes of anemia in infrequent blood donors deferred for low hemoglobin (Hb) are not well known. We sought to assess this via surveys of infrequent, nonmenstruating deferred blood donors at two institutions, BloodCenter of Wisconsin and Puget Sound Blood Center.Study Design and MethodsMen at least 18 years of age and women at least 50 years of age who were deferred for low Hb (≤12.5 g/dL), had not more than one donation in the year prior to deferral, and did not successfully donate in the 3 months after their deferral were surveyed.ResultsThe total response rate was 380 donors or 34% of those contacted. Of the respondents, 141 had sought medical advice about their low Hb. Of these, 90 were confirmed to have anemia and 13 reported serious disease requiring medical intervention, including mantle cell lymphoma, multiple myeloma, and gastrointestinal bleeding.ConclusionsA small but concerning number of infrequent blood donors deferred for low Hb have an underlying illness that is severe and would benefit from medical attention. Donors deferred for low Hb who have a high risk for serious underlying illness should be provided targeted educational information advising them to seek additional medical care.