Activity changes of glyoxalases I-II and glutathione reductase in regenerating rat liver.
Activity changes of glyoxalases I-II and glutathione reductase in regenerating rat liver.
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再生大鼠肝脏中乙二醛酶 I-II 和谷胱甘肽还原酶的活性变化。
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
E. Giovannini
中科院分区：
文献类型：
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作者：
G. Principato;P. Locci;G. Rosi;V. Talesa;E. Giovannini
在再生的大鼠肝中，部分肝切除术后24-48小时，谷胱甘肽酶I活性显示出显著增加。在手术后16、48和72小时，谷胱甘肽酶II活性显著增加，并且在24小时显示出短暂的降低。肝再生过程中观察到的Glycosidase I和II活性变化可能与这些酶的不同作用相关。在手术后8-72小时内显著降低的谷胱甘肽还原酶活性与谷胱甘肽酶没有任何相关性。这些研究的酶活性在假手术动物中未显示出显著变化。
In regenerating rat liver Glyoxalase I activity shows a significant increase 24-48 hrs after partial hepatectomy. Glyoxalase II activity is significantly increased at 16, 48, and 72 hrs, and shows a transient decrease at 24 hrs after surgery. It is likely that the observed changes in Glyoxalases I and II activities during hepatic regeneration are correlated with the different roles of these enzymes. Glutathione reductase activity, significantly reduced within 8-72 hrs after surgery, does not show any correlation with Glyoxalases. These studied enzyme activities do not display significant changes in the sham-operated animals.