Validation of a Culturally Relevant Snakebite Envenomation Clinical Practice Guideline in Brazil.
Validation of a Culturally Relevant Snakebite Envenomation Clinical Practice Guideline in Brazil.
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蛇咬伤（SBE）是一种被忽视的热带疾病，具有显著的全球发病率和死亡率。即使在资源匮乏的地区有抗蛇毒血清，卫生工作者也没有接受足够的培训来管理sbe。本研究旨在制定和验证巴西SBE管理的临床实践指南（CPG）。在SBE管理方面具有学术和/或技术专长的专家评审小组执行内容验证。CPG目标的内容效度指数（CVI）得分为90%，结构和表现为89%，相关性为92%，并将CPG分类为有效。在为期5天的CPG会议后，通过分析来自巴西亚马逊三个城市的医生和护士的焦点小组讨论，进行了语义验证。出现了两个中心主题：在会议期间获得的知识和关于改进CPG的建议。基于这些结果，CPG被修订为最终版本。本研究提出了一种针对特定低资源、高负担环境的SBE管理CPG的成功开发和验证过程。这种开发和验证过程可以适用于其他环境和/或其他被忽视的热带病。
Snakebite envenoming (SBE) is a neglected tropical disease with significant global morbidity and mortality. Even when antivenom is available in low-resource areas, health workers do not receive adequate training to manage SBEs. This study aims to develop and validate a clinical practice guideline (CPG) for SBE management across Brazil. A panel of expert judges with academic and/or technical expertise in SBE management performed content validation. The content validity index (CVI) score was 90% for CPG objectives, 89% for structure and presentation and 92% for relevance and classified the CPG as valid. A semantic validation was performed by analyzing focus group discussions with doctors and nurses from three municipalities of the Brazilian Amazon, after a 5-day meeting during which the CPG was presented. Two central themes emerged: knowledge acquired during the meeting and recommendations for improving the CPG. Based on these results, the CPG was revised into a final version. This study presents the successful development and validation process of a CPG for SBE management, which is targeted to a specific low-resource, high-burden setting. This development and validation process can be adapted to other settings and/or other neglected tropical diseases.
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影响因子：
3.8
作者：
Sapkota S;Pandey DP;Dhakal GP;Gurung DB
通讯作者：
Gurung DB
影响因子：
3.8
作者：
Williams, David J.;Abul Faiz, Mohd;Warrell, David A.
通讯作者：
Warrell, David A.
影响因子：
1.4
作者：
Gaus, David P.;Herrera, Diego F.;Guevara, Alicia H.
通讯作者：
Guevara, Alicia H.
影响因子：
3.3
作者：
de Oliveira, Samella Silva;Alves, Eliane Campos;Monteiro, Wuelton Marcelo
通讯作者：
Monteiro, Wuelton Marcelo
影响因子：
--
作者：
Potet J;Beran D;Ray N;Alcoba G;Habib AG;Iliyasu G;Waldmann B;Ralph R;Faiz MA;Monteiro WM;de Almeida Gonçalves Sachett J;di Fabio JL;Cortés MLÁ;Brown NI;Williams DJ
通讯作者：
Williams DJ