A Comparison of Egg Consumption with Other Modifiable Coronary Heart Disease Lifestyle Risk Factors: A Relative Risk Apportionment Study

A Comparison of Egg Consumption with Other Modifiable Coronary Heart Disease Lifestyle Risk Factors: A Relative Risk Apportionment Study
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DOI:
10.1111/j.1539-6924.2008.01149.x
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发表时间:
2009-03-01
期刊:
影响因子:
3.8
通讯作者:
Mink, Pamela
Mink, Pamela
中科院分区:
医学3区
文献类型:
--
作者:
Barraj, Leila;Tran, Nga;Mink, Pamela

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美国心脏协会(AHA)的指南建议健康成年人将膳食胆固醇的摄入量限制在每天300毫克以下。由于一个大鸡蛋含有大约71%的胆固醇,AHA建议限制鸡蛋的消费,除非其他来源的饮食胆固醇摄入量受到限制。我们应用风险分配方法来估计鸡蛋消费和其他可改变的生活方式风险因素(例如,吸烟、不良饮食、最少运动和酒精摄入)与人群水平的冠心病(CHD)风险之间的关系。具体来说,我们根据可改变的生活方式风险因素的患病率将25岁以上的美国成年人分为不同的风险组,并应用分配模型(通常用于评估个体水平的风险贡献)来估计鸡蛋摄入对CHD风险的贡献。我们的分析表明,可改变的生活方式危险因素的组合占不到40%的人群CHD死亡率。对于大多数25岁以上的美国成年人来说,每天吃一个鸡蛋占CHD风险的1%。因此,专注于减少鸡蛋摄入量作为改变CHD风险的一种方法,预计相对于改变其他行为(如吸烟和其他饮食习惯),将产生最小的结果。
Guidelines from the American Heart Association (AHA) recommend that healthy adults limit their intake of dietary cholesterol to less than 300 mg per day. Since a large egg contains about 71% of that amount, the AHA recommends restricting egg consumption unless dietary cholesterol intakes from other sources are limited. We applied a risk apportionment approach to estimate the contribution of egg consumption and other modifiable lifestyle risk factors (e.g., smoking, poor diet, minimal exercise, and alcohol intake) to coronary heart disease (CHD) risk at the population level. Specifically, we categorized the U.S. adult population ages 25+ into distinct risk groups based on the prevalence of modifiable lifestyle risk factors and applied an apportionment model, typically used to assess risk contribution at the individual level, to estimate the contribution of egg intake to CHD risk. Our analysis shows that the combination of modifiable lifestyle risk factors accounts for less than 40% of the population CHD mortality. For the majority of U.S. adults age 25+, consuming one egg a day accounts for < 1% of CHD risk. Hence, focusing on decreasing egg intake as an approach to modify CHD risk would be expected to yield minimal results relative to changing other behaviors such as smoking and other dietary habits.