Trier Social Stress Test in Indian Adolescents
Trier Social Stress Test in Indian Adolescents
复制标题
DOI：
10.1007/s13312-014-0437-5
复制
发表时间：
2014-06-01
影响因子：
2.3
通讯作者：
Fall, C. H. D.
中科院分区：
文献类型：
--
作者：
Krishnaveni, G. V.;Veena, S. R.;Fall, C. H. D.
目的：在印度青少年队列中测试特里尔儿童社会压力测试（TSST-C）。设计：队列研究。设置：印度迈索尔的Holdsworth纪念医院。参与者：青少年儿童（N=273，134名男性;平均年龄13.6岁）从正在进行的出生队列中选择; 269名完成了测试。在两个不熟悉的“评估者”面前进行5分钟的公开演讲和心算任务。结果测量：在基线和TSST-C后定期测量唾液皮质醇浓度。使用指套在TSST-C之前、期间和之后10分钟进行心率、手指血压、每搏输出量、心输出量和全身血管阻力的连续测量。6.1（6.9）ng/mL]，心率[4.6（10.1）bpm]，收缩压[24.2（11.6）mmHg]和舒张压[16.5心输出量[0.6（0.7）L/min]、每搏输出量[4.0（5.6）mL]和体循环血管阻力[225（282）dyn.s/cm（5）]显著增加（P
Objective: To test the Trier Social Stress Test for children (TSST-C) in a cohort of Indian adolescents.Design: Cohort studySetting: Holdsworth Memorial Hospital, Mysore, India.Participants: Adolescent children (N=273, 134 Males; mean age 13.6 yrs) selected from an ongoing birth cohort; 269 completed the test.Intervention: Performance of 5-minutes each of public- speaking and mental arithmetic tasks in front of two unfamiliar 'evaluators'.Outcome measures: Salivary cortisol concentrations were measured at baseline and at regular intervals after the TSST-C. Continuous measurements of heart rate, finger blood pressure, stroke volume, cardiac output and systemic vascular resistance were carried out before, during and for 10 minutes after the TSST-C using a finger cuff.Results: Cortisol concentrations [mean increment (SD): 6.1 (6.9) ng/mL], heart rate [4.6 (10.1) bpm], systolic [24.2 (11.6) mmHg] and diastolic blood pressure [16.5 (7.3) mmHg], cardiac output [0.6 (0.7) L/min], stroke volume [4.0 (5.6) mL] and systemic vascular resistance [225 (282) dyn.s/cm(5)] increased significantly (P