Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor
Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor
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DOI：
10.1007/s00330-010-2044-8
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发表时间：
2011-06-01
影响因子：
5.9
通讯作者：
Stoker, J.
中科院分区：
文献类型：
--
作者：
Zijta, F. M.;Froeling, M.;Stoker, J.
前瞻性地确定弥散张量成像 (DTI) 与纤维束成像作为正常盆底解剖结构三维 (3D) 可视化工具的可行性。五名年轻女性初产受试者（平均年龄 28 +/- 3 岁）接受了 3.0T 的 DTI。对盆底进行二维扩散加权轴向自旋回波平面回波 (SP-EPI) 脉冲序列，并附加 T2-TSE 多平面序列作为解剖学参考。两名观察者采用一致方法离线进行纤维束成像，以可视化预定义的盆底和盆壁肌肉。根据纤维轨迹计算三个特征值（lambda 1、lambda 2、lambda 3）、分数各向异性（FA）和平均扩散率（MD）。在所有受试者中，纤维束成像都获得了耻骨内脏肌、会阴体、肛门和尿道括约肌复合体以及闭孔内肌的令人满意的解剖学表现。平均 FA 值范围为 0.23 +/- 0.02 至 0.30 +/- 0.04，MD 值范围为 1.30 +/- 0.08 至 1.73 +/- 0.12 x 10(-)A(3)aEuro 千分之一 mmA(2)/s。盆底浅层的肌肉结构无法令人满意地识别。本研究证明了使用 3T-DTI 和纤维束成像技术可视化复杂的三维盆底结构的可行性。女性盆底深处的 DTI 可能为盆底疾病提供新的见解。
To prospectively determine the feasibility of diffusion tensor imaging (DTI) with fibre tractography as a tool for the three-dimensional (3D) visualisation of normal pelvic floor anatomy.Five young female nulliparous subjects (mean age 28 +/- 3 years) underwent DTI at 3.0T. Two-dimensional diffusion-weighted axial spin-echo echo-planar (SP-EPI) pulse sequence of the pelvic floor was performed, with additional T2-TSE multiplanar sequences for anatomical reference. Fibre tractography for visualisation of predefined pelvic floor and pelvic wall muscles was performed offline by two observers, applying a consensus method. Three eigenvalues (lambda 1, lambda 2, lambda 3), fractional anisotropy (FA) and mean diffusivity (MD) were calculated from the fibre trajectories.In all subjects fibre tractography resulted in a satisfactory anatomical representation of the pubovisceral muscle, perineal body, anal - and urethral sphincter complex and internal obturator muscle. Mean FA values ranged from 0.23 +/- 0.02 to 0.30 +/- 0.04, MD values from 1.30 +/- 0.08 to 1.73 +/- 0.12 x 10(-)A(3)aEuro parts per thousand mmA(2)/s. Muscular structures in the superficial layer of the pelvic floor could not be satisfactorily identified.This study demonstrates the feasibility of visualising the complex three-dimensional pelvic floor architecture using 3T-DTI with fibre tractography. DTI of the deep female pelvic floor may provide new insights into pelvic floor disorders.