Sex-specific odorant receptors of the tobacco hornworm Manduca sexta
Sex-specific odorant receptors of the tobacco hornworm Manduca sexta
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DOI：
10.3389/fncel.2010.00022
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发表时间：
2010-08-01
影响因子：
5.3
通讯作者：
Hansson, Bill S.
中科院分区：
文献类型：
--
作者：
Grosse-Wilde, Ewald;Stieber, Regina;Hansson, Bill S.
由于气味信息在蛾类的生活中起着至关重要的作用，蛾类的嗅觉已经进化成为一种高度特异和敏感的与繁殖和生存有关的器官。气味检测的关键参与者是嗅觉受体（OR）蛋白。在这里，我们确定了四个OR编码基因差异表达的触角的男性和女性的天蛾天蛾。两个雄性特异性受体（以前报道的MsexOR-1和新鉴定的MsexOR-4）显示出与其他雄蛾信息素OR的极大相似性。推定的信息素受体与参与一般气味信号转导的共受体DmelOr 83 b同源物MsexOR-2共表达。一种雌性特异性受体（MsexOR-5）与BmorOR-19相似，BmorOR-19是一种在家蚕中被调谐为检测植物气味芳樟醇的受体。
As odor information plays a vital role in the life of moths, their olfactory sense has evolved into a highly specific and sensitive apparatus relevant to reproduction and survival. The key players in the detection of odorants are olfactory receptor (OR) proteins. Here we identify four OR-encoding genes differentially expressed in the antennae of males and females of the sphingid moth Manduca sexta. Two male-specific receptors (the previously reported MsexOR-1 and the newly identified MsexOR-4) show great resemblance to other male moth pheromone ORs. The putative pheromone receptors are co-expressed with the co-receptor involved in general odorant signal transduction, the DmelOr83b homolog MsexOR-2. One female-specific receptor (MsexOR-5) displays similarities to BmorOR-19, a receptor in Bombyx mori tuned to the detection of the plant odor linalool.