SEGMENTAL DETERMINATION IN DROSOPHILA CENTRAL NERVOUS-SYSTEM
SEGMENTAL DETERMINATION IN DROSOPHILA CENTRAL NERVOUS-SYSTEM
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DOI：
10.1016/0092-8674(85)90354-x
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发表时间：
1985-01-01
期刊：
影响因子：
64.5
通讯作者：
JAN, YN
中科院分区：
文献类型：
--
作者：
GHYSEN, A;JAN, LY;JAN, YN
分析了果蝇幼虫中枢神经系统中2个节段特异性特征的控制。其中一个只存在于幼虫的胸神经节中，在那里它代表了成年腿神经节的原基;另一个在第一腹部以及胸神经节中发现。双胸复合体内的突变对这些神经结构和幼虫表皮具有平行但独立的影响。中枢神经系统对双胸复合体的轻微扰动非常敏感，尤其是对单倍功能不全。
The control of 2 segment-specific features in the CNS of Drosophila larvae were analyzed. One of them is present only in the thoracic ganglia of the larva, where it represents the anlage of the adult leg neuromeres; the other is found in the first abdominal, as well as in the thoracic, ganglia. Mutations within the bithorax complex have parallel but independent effects on these neural structures and on the larval epidermis. The CNS is very sensitive to mild perturbations of the bithorax complex, and in particular to haploinsufficiency.