Responses of sympathetic outflow to skin during caloric stimulation in humans
Responses of sympathetic outflow to skin during caloric stimulation in humans
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DOI：
10.1152/ajpregu.1999.276.3.r738
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发表时间：
1999-03-01
影响因子：
2.8
通讯作者：
Kitazawa, H
中科院分区：
文献类型：
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作者：
Cui, J;Iwase, S;Kitazawa, H
我们先前的研究表明，前庭的卡路里刺激引起人类交感神经流出到肌肉(MSNA)增加。本研究旨在探讨这种刺激对交感神经皮肤流出(SSNA)的影响。9名受试者用50毫升冷水(10℃)或温水(44℃)冲洗外道时，记录了胫神经、腓神经和眼球震颤的SSNA。眼球震颤时，胫神经和腓神经的SSNA分别降至50+/-48(基线值为100%)和61+/-4%。两神经SSNA抑制程度与眼球震颤最大慢相速度成正比。眼球震颤后，SSNA分别增加到166+/-7和168+/-6%，晕动病症状的程度与SSNA增加有关。这些结果表明，前庭冷热刺激时的SSNA反应与MSNA反应不同，前庭冷热刺激初期的SSNA反应不同于运动病症状期的SSNA反应。
We previously showed that caloric vestibular stimulation elicits increases in sympathetic outflow to muscle (MSNA) in humans. The present study was conducted to determine the effect of this stimulation on sympathetic outflow to skin (SSNA). The SSNA in the tibial and peroneal nerves and nystagmus was recorded in nine subjects when the external meatus was irrigated with 50 ml of cold (10 degrees C) or warm (44 degrees C) water. During nystagmus, the SSNA in tibial and peroneal nerves decreased to 50 +/- 48 (with baseline value set as 100%) and 61 +/- 4%, respectively. The degree of SSNA suppression in both nerves was proportional to the maximum slow-phase velocity of nystagmus. After nystagmus, the SSNA increased to 166 +/- 7 and 168 +/- 6%, respectively, and the degree of motion sickness symptoms was correlated with this SSNA increase. These results suggest that the SSNA response differs from the MSNA response during caloric vestibular stimulation and that the SSNA response elicited in the initial period of caloric vestibular stimulation is different from that observed during the period of motion sickness symptoms.