Micromachined "Side-Viewing" Optical Sensor Probe for Detection of Esophageal Cancers.
Micromachined "Side-Viewing" Optical Sensor Probe for Detection of Esophageal Cancers.
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用于检测食道癌的微机械“侧视”光学传感器探头。
DOI：
10.1016/j.sna.2008.11.008
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Wang,LV
中科院分区：
文献类型：
--
作者：
Garcia-Uribe,A;Balareddy,KC;Zou,J;Wojcik,AK;Wang,KK;Wang,LV
在本文中，我们报告了一种新型微型光学传感器探头的设计、制造和测试，该探头具有“侧视”功能，用于斜入射漫反射光谱测定。该传感器探头由光刻图案化聚合物波导芯片和两个微机械定位基板以及源/收集光纤组成，以实现 45° 光入射和空间分辨漫反射的收集。已成功测量人类食管表面的漫反射率，以区分癌组织与正常组织。
In this paper, we report the design, fabrication and testing of a new miniaturized optical sensor probe with “side viewing” capability for oblique incidence diffuse reflectance spectrometry. The sensor probe consists of a lithographically patterned polymer waveguides chip and two micromachined positioning substrates and source/collection fibers to achieve 45° light incidence and collection of spatially resolved diffuse reflectance. Diffuse reflectance of human esophageal surface has been successfully measured for differentiation of cancerous tissues from normal ones.