Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.

Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.
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组蛋白脱乙酰酶抑制剂 depsipeptide (FK228) 通过促进 Bax 的线粒体易位诱导白血病细胞凋亡,蛋白酶体抑制剂硼替佐米可增强这种易位。

DOI:
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发表时间:
2006
期刊:
Acta Haematol. 115・1-2
影响因子:
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通讯作者:
K.
K.
中科院分区:
--
文献类型:
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作者:
Sutheesophon;K.

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