HEMOGLOBIN DISORDERS - A PATTERN FOR THALASSEMIA AND HEMOGLOBINOPATHIES IN ARABIA
HEMOGLOBIN DISORDERS - A PATTERN FOR THALASSEMIA AND HEMOGLOBINOPATHIES IN ARABIA
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DOI：
10.1159/000206947
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发表时间：
1982-01-01
影响因子：
2.4
通讯作者：
ELHAZMI, MAF
中科院分区：
文献类型：
--
作者：
ELHAZMI, MAF
阿拉伯血红蛋白病和地中海贫血的温和病程以及遗传异常和环境因素的相互作用特别令人感兴趣，因为半岛呈现出多样的气候和地形，鼓励研究各种遗传和环境因素之间的相互作用。本研究旨在阐明沙特阿拉伯各地区这些遗传异常的发生率和频率。阐明了血红蛋白病、地中海贫血和葡萄糖-6-磷酸脱氢酶缺乏症与疟原虫的关系。结果是根据该地区普遍存在的环境因素呈现的。
The mild disease course of the hemoglobinopathies and thalassemias in Arabia and the interaction of the genetic abnormality and environmental factors are particularly interesting, as the peninsula exhibits a diverse climate and topography that encourages study of the interactions between various genetic and environmental factors. The present study is aimed at elucidating the incidence and frequency of these genetic abnormalities in various regions of Saudi Arabia. The relationship between hemoglobinopathies, thalassemia and glucose-6-phosphate dehydrogenase deficiency and malaria parasites were elucidated. The results are presented in light of the environmental factors prevailing in the area.