Joint intracranial and carotid vessel wall imaging in 5 minutes using compressed sensing accelerated DANTE-SPACE
Joint intracranial and carotid vessel wall imaging in 5 minutes using compressed sensing accelerated DANTE-SPACE
复制标题
使用压缩传感加速 DANTE-SPACE 在 5 分钟内完成颅内和颈动脉血管壁联合成像
DOI：
10.1007/s00330-019-06366-7
复制
发表时间：
2020-01-01
影响因子：
5.9
通讯作者：
Chung, Yiu-cho
中科院分区：
文献类型：
--
作者：
Jia, Sen;Zhang, Lei;Chung, Yiu-cho
目的比较5倍压缩感知加速三维DANTE-SPACE序列（CS VWI）和2.7倍平行成像（PI VWI）在5分钟内获得的关节颅内和颈动脉血管壁的可视化效果，并行成像目前需要9-10分钟。方法经机构审查委员会批准和知情同意，对28例脑卒中患者（包括20例）进行PI和CS VWI检查，获得各向同性0.55 mm的空间分辨率，颅内和颈动脉关节覆盖。分别比较健康志愿者和壁增厚患者的CS VWI和PI VWI定量壁厚测量值。两种VWI方法对患者的主观壁可视化由两名放射科医生盲目和独立地使用4分制评分，然后进行评分间可重复性分析。结果对壁厚测量值进行线性回归分析，发现健康志愿者（r = 0.99）和脑卒中壁增厚患者（r = 0.99）的CS VWI和PI VWI具有很好的一致性。CS VWI主观壁显示评分略低于PI VWI (3.13 +/- 0.41 vs. 3.31 +/- 0.79)，但仍具有较好的诊断质量（4分制>.3）。两名放射科医生的评分非常一致，类内相关系数（ICC）值均高于0.75 （p < 0.001）。结论压缩传感技术可在5分钟内以0.55 mm的各向同性分辨率获得关节颅内和颈动脉VWI，且不影响定量血管壁厚度测量或诊断性壁可视化。
Objectives To compare visualization of joint intracranial and carotid vessel walls between 5x compressed sensing accelerated three-dimensional DANTE-SPACE sequence (CS VWI) acquired in 5 min and the same sequence accelerated by 2.7x parallel imaging (PI VWI) which takes 9-10 min currently. Methods Following institutional review board approval and informed consent, 28 subjects including 20 stroke patients underwent PI and CS VWI examinations with an acquired spatial resolution of isotropic 0.55 mm and joint coverage of intracranial and carotid arteries. Quantitative wall thickness measurements of CS VWI and PI VWI were compared on healthy volunteers and patients with wall thickening respectively. Subjective wall visualizations of the two VWI methods on patients were scored by two radiologists blindly and independently using a 4-point scale followed by inter-rater reproducibility analysis. Results Linear regression analysis of wall thickness measurements showed excellent agreement between CS VWI and PI VWI in both healthy volunteers (r = 0.99) and stroke patients with wall thickening (r = 0.99). Subjective wall visualization score of CS VWI was slightly lower than PI VWI (3.13 +/- 0.41 vs. 3.31 +/- 0.79) but still had good diagnostic quality (> 3 based on a 4-point scale). The two radiologists' scores agreed excellently, evidenced by the intraclass correlation coefficient (ICC) values being higher than 0.75 (p < 0.001). Conclusions Compressed sensing expedients joint intracranial and carotid VWI acquired at an isotropic resolution of 0.55 mm in 5 min without compromising quantitative vessel wall thickness measurement or diagnostic wall visualization.