Ultrasonic hyperthermia and radiation in the management of intraocular malignant melanoma.
Ultrasonic hyperthermia and radiation in the management of intraocular malignant melanoma.
复制标题
超声热疗和放射治疗眼内恶性黑色素瘤。
DOI：
10.1016/0002-9394(86)90761-0
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发表时间：
1986
影响因子：
4.2
通讯作者：
Abramson,DH
中科院分区：
文献类型：
--
作者：
Coleman,DJ;Lizzi,FL;Burgess,SE;Silverman,RH;Smith,ME;Driller,J;Rosado,A;Ellsworth,RM;Haik,BG;Abramson,DH
采用热疗联合放射治疗4例脉络膜恶性黑色素瘤。该技术使用超声诱导的高温与辐射协同作用来破坏肿瘤细胞。较低水平的辐射使用应避免在传统的放射治疗中看到的晚期血管和炎症并发症，肿瘤被扫描的计算机化诊断超声系统治疗前，并分配一个声学组织类型的基础上，统计比较其超声背向散射光谱与光谱的肿瘤已知的病理状态。在随访期间，其中最长的是15个月，所有的肿瘤表现出与传统放射治疗相同的听组织类型的脉络膜肿瘤一致的回归模式。
Hyperthermia and radiation were used in combination to treat four patients with choroidal malignant melanoma. This technique uses ultrasonically induced hyperthermia synergistically with radiation to destroy tumor cells. The lower levels of radiation used should avoid the late vascular and inflammatory complications seen in conventional radiation therapy.Tumors were scanned by a computerized diagnostic ultrasound system before treatment and assigned an acoustic tissue type on the basis of a statistical comparison of their ultrasound backscatter spectrum with spectra of tumors of known pathologic status. During the follow-up period, the longest of which was 15 months, all tumors demonstrated regression patterns consistent with choroidal tumors of the same acoustic tissue types treated with conventional radiation therapy.