Direct chemiluminescence detection of circulating microRNAs in serum samples using a single-strand specific nuclease-distinguishing nucleic acid hybrid system

Direct chemiluminescence detection of circulating microRNAs in serum samples using a single-strand specific nuclease-distinguishing nucleic acid hybrid system
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使用单链特异性核酸酶区分核酸杂交系统直接化学发光检测血清样品中的循环 microRNA

DOI:
10.1039/c7cc09087k
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发表时间:
2018-02-21
影响因子:
4.9
通讯作者:
Li, Fu-Rong
Li, Fu-Rong
中科院分区:
化学2区
文献类型:
--
作者:
Ling, Kai;Jiang, Hongyan;Li, Fu-Rong

文献摘要

被引文献

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我们开发了一种基于微孔板的增强化学发光系统,用于直接检测循环miRNA。该系统具有较高的目标灵敏度和特异性,检测限为3.02 fM。
We developed a microplate-based enhanced chemiluminescence system for the direct detection of circulating miRNAs. The system exhibited a high target sensitivity and specificity, with a detection limit of 3.02 fM.