Internet intervention for increasing physical activity in persons with multiple sclerosis
Internet intervention for increasing physical activity in persons with multiple sclerosis
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DOI：
10.1177/1352458510383148
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发表时间：
2011-01-01
影响因子：
5.8
通讯作者：
Mohr, David C.
中科院分区：
文献类型：
--
作者：
Motl, Robert W.;Dlugonski, Deirdre;Mohr, David C.
背景：体力活动与多发性硬化症（MS）患者步行活动能力和生活质量的改善有关，然而与普通人群相比，这一人群在很大程度上是久坐不动的。目的：我们进行了一项试点、随机对照试验（RCT），以检验基于社会认知理论（SCT）的互联网干预对增加多发性硬化症患者身体活动的有利影响。我们进一步研究了SCT变量作为互联网干预的可能中介。方法：我们将54名多发性硬化症患者随机分配到网络干预组和候补对照组。参与者在12周前后完成了身体活动、自我效能、结果预期、功能限制和目标设定的测量。结果：干预组患者体力活动随时间的增加有统计学意义（p = 0.01）且增加幅度较大（d = 0.72），对照组患者体力活动变化较小（d = 0.04）且无统计学意义（p = 0.71）。干预组进一步报告了具有统计学意义（p = 0.001）且随着时间的推移目标设定大幅增加（d = 0.97），而对照组则有较小（d =-0.13）且无显著变化（p = 0.17）。目标设定随时间的改变在网络干预对身体活动行为的影响中起中介作用。结论：该初步研究为后续的RCT奠定了基础，该RCT包括更大的MS患者样本，更长的干预期和随访，客观测量身体活动，以及步行活动和生活质量的次要结果。
Background: Physical activity has been associated with improvements in walking mobility and quality of life in persons with multiple sclerosis (MS), and yet this population is largely sedentary and inactive compared with the general population.Objectives: We conducted a pilot, randomized controlled trial (RCT) for examining the effect of an Internet intervention based on social cognitive theory (SCT) for favorably increasing physical activity among persons with MS. We further examined variables from SCT as possible mediators of the Internet intervention.Methods: We randomly allocated 54 persons with MS into either an Internet intervention condition or a waitlist control condition. The participants completed measures of physical activity, self-efficacy, outcome expectations, functional limitations, and goal setting before and after the 12-week period.Results: The intervention group reported a statistically significant (p = 0.01) and large increase in physical activity over time (d = 0.72), whereas the control group had a small (d = 0.04) and non-significant change in physical activity (p = 0.71). The intervention group further reported a statistically significant (p = 0.001) and large increase in goal setting over time (d = 0.97), whereas the control group had a small (d =-0.13) and non-significant change (p = 0.17). The change in goal setting over time mediated the effect of the Internet intervention on physical activity behavior.Conclusions: This pilot study sets the stage for a subsequent RCT that includes a larger sample of persons with MS, longer intervention period along with a follow-up, objective measure of physical activity, and secondary outcomes of walking mobility and QOL.