Methadone in pregnancy: treatment retention and neonatal outcomes
Methadone in pregnancy: treatment retention and neonatal outcomes
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DOI：
10.1111/j.1360-0443.2006.01651.x
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发表时间：
2007-02-01
期刊：
影响因子：
6
通讯作者：
Wallace, Cate
中科院分区：
文献类型：
--
作者：
Burns, Lucy;Mattick, Richard P.;Wallace, Cate
目的研究妊娠期美沙酮治疗的保留与关键新生儿结局之间的关系。新南威尔士州药物成瘾系统的设计客户数据与1992年至2002年新南威尔士州助产士数据收集和新南威尔士州住院病人统计收集的出生信息相关联。测量产科和围产期的妇女谁保留在整个怀孕期间持续美沙酮维持的特点进行了比较，那些谁进入晚在他们的怀孕（不到6个月前出生）和那些最后一次治疗事件结束至少一年前出生。结果-有2993出生的妇女记录为美沙酮在分娩时，从1992年的62增加到2002年的459出生。与在整个怀孕期间持续服用美沙酮的母亲相比，那些晚接受治疗的母亲也晚接受产前服务，更有可能在未预约的情况下到达医院分娩，更经常未婚，土著和吸烟更多。晚入学新生的比例较高，出生在不到3 - 7周的妊娠，并承认特殊护理托儿所更频繁。结论妊娠期持续美沙酮治疗与早期产前保健和改善新生儿结局有关。应确定和实施创新技术，使使用海洛因的怀孕妇女或计划怀孕的妇女尽早接受美沙酮治疗。
Aim To examine the association between retention in methadone treatment during pregnancy and key neonatal outcomes. Design Client data from the New South Wales Pharmaceutical Drugs of Addiction System was linked to birth information from the NSW Midwives Data Collection and the NSW Inpatient Statistics Collection from 1992 to 2002. Measurements Obstetric and perinatal characteristics of women who were retained continuously on methadone maintenance throughout their pregnancy were compared to those who entered late in their pregnancies (less than 6 months prior to birth) and those whose last treatment episode ended at least I year prior to birth. Findings There were 2993 births to women recorded as being on methadone at delivery, increasing from 62 in 1992 to 459 births in 2002. Compared to mothers who were maintained continuously on methadone throughout their pregnancy, those who entered treatment late also presented later to antenatal services, were more likely to arrive at hospital for delivery unbooked, were more often unmarried, indigenous and smoked more heavily. A higher proportion of neonates born to late entrants Were born at less than 3 7 weeks gestation and were admitted to special care nursery more often. Conclusion Continuous methadone treatment during pregnancy is associated with earlier antenatal care and improved neonatal outcomes. Innovative techniques for early engagement in methadone treatment by pregnant heroin using Women or those planning to become pregnant should be identified and implemented.