EPOXOMICIN, A NEW ANTITUMOR AGENT OF MICROBIAL ORIGIN
EPOXOMICIN, A NEW ANTITUMOR AGENT OF MICROBIAL ORIGIN
复制标题
DOI：
10.7164/antibiotics.45.1746
复制
发表时间：
1992-11-01
影响因子：
3.3
通讯作者：
OKI, T
中科院分区：
文献类型：
--
作者：
HANADA, M;SUGAWARA, K;OKI, T
放线菌Q996-17产生一种新化合物环氧霉素，该化合物对B16黑色素瘤具有体内抗肿瘤活性。结构研究表明，它是环氧-β-氨基酮基团的新成员，与eponemycin密切相关。
An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-beta-aminoketone group, and is closely related to eponemycin.