Green and Efficient Synthesis of Thiophosphinates, Thiophosphates, and Thiophosphinites in Water
Green and Efficient Synthesis of Thiophosphinates, Thiophosphates, and Thiophosphinites in Water
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DOI：
10.1002/slct.201903995
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发表时间：
2019-12
期刊：
影响因子：
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通讯作者：
Guanghui Wang;Lihong Zhou;Nutao Li;Qingle Zeng
中科院分区：
文献类型：
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作者：
Guanghui Wang;Lihong Zhou;Nutao Li;Qingle Zeng
研究了在水中，H-膦氧化物、H-膦酸酯和二芳基膦与N-（芳基/烷硫基）琥珀酰亚胺的无金属交叉偶联反应。该方案以中等至优异的产率提供了硫代次膦酸酯、硫代磷酸酯和硫代次膦酸酯的更绿色的合成。该反应的机理可能涉及亲核取代和自由基反应。
A metal‐free cross‐coupling reaction of H‐phosphine oxides, H‐phosphonate esters, and diarylphosphines with N‐(aryl/alkylthio)succinimides in water was developed. This protocol provides a greener synthesis of thiophosphinates, thiophosphates, and thiophosphinites in moderate to excellent yields. The mechanism of this reaction probably involves nucleophilic substitution and free radical reactions.