Hypothermia after cardiac arrest - Experiences in routine use on a medical intensive care unit

Hypothermia after cardiac arrest - Experiences in routine use on a medical intensive care unit
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DOI:
10.1007/s00390-007-0775-9
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发表时间:
2007-06-01
期刊:
Intensivmedizin und Notfallmedizin
影响因子:
--
通讯作者:
Heer, C.
Heer, C.
中科院分区:
其他
文献类型:
--
作者:
Heer, C.

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Background The extent of hypoxia - induced cerebral damage essentially determines prognosis after survived cardiac arrest. Two multicenter studies have proven the positive effect of mild hypothermia on neurological outcome. Based on these studies ILCOR recommended in 2003 the cooling of sustained unconscious adults after effective resuscitation. Hypothermia was implemented in 2003 as a new method and is currently routinely used in our medical intensive care unit. Methods We compared the clinical outcome of 38 cooled patients with 38 not cooled patients from the period before this therapy was implemented. Cooling was performed in 32 patients by an intravasal cooling catheter and in 6 patients by cooling mats. The cooling was maintained for 24 h with a core temperature of 33 degrees C. Results In both groups the most frequent cause of cardiac arrest was ventricular fibrilliation. By using hypothermia the number of patients with severe neurological damage decreased from 39% to 16% and vice versa the number of those without a neurological deficit increased from 11% to 32%. Conclusions Our data suggest that hypothermia after cardiac resuscitation in the routine use in normal course of medical intensive care is an effective method to improve neurological outcome.