Mating‐regulates reproductive‐tract neuromodulators in Drosophila
Mating‐regulates reproductive‐tract neuromodulators in Drosophila
复制标题
交配调节果蝇的生殖道神经调节剂
DOI：
10.1002/mrd.22338
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发表时间：
2014
影响因子：
2.5
通讯作者：
Wolfner,MarianaF
中科院分区：
文献类型：
--
作者：
Heifetz,Yael;Wolfner,MarianaF
交配调节果蝇生殖道区域神经调节剂的可用组合。这导致神经调节剂的组合“代码”随着地点和时间的变化而变化，并被提议协调生殖道的功能变化，以响应交配（当代生物学，24,731-737）。这些假色图像显示了未交配的雌性或交配后不同时间雌性果蝇生殖道不同区域的章鱼胺、血清素、肌抑制素或nNOS免疫反应性。上图显示未交配雌性的精囊（加上右图中较低的普通输卵管），染色为n-NOS。第二行显示雌性与缺乏精液蛋白的雄性交配后（分别在交配后20分钟和180分钟）的精囊、子宫（左图）和精囊（右图）的n-NOS染色。第三行是雌性与野生型雄性交配24小时后子宫（左图中还有精囊）的章鱼胺染色。最下面一行显示的是雌性与野生型雄性交配后的常见输卵管。左图为交配后90度的fmrfamilydromyosuppressin染色；右图为交配后180分钟的血清素染色。图片由Zohar Nir-Amitin提供。
Mating regulates the available combinations of neuromodulators in Drosophila reproductivetract regions. This results in a combinatorial “code” of neuromodulators that changes with place and time, and is proposed to coordinate functional changes along the reproductive tract in response to mating (Current Biology. 24, 731–737). These false-colored images show octopamine, serotonin, dromyosuppressin, or nNOS immunoreactivity in different regions of the Drosophila reproductive tracts of unmated females or of females at different times post-mating.The top row shows seminal receptacles (plus lower common oviduct in the image on the right) of unmated females, stained for n-NOS. The second row shows n-NOS staining of a seminal receptacle and uterus (left image) and seminal receptacle (right image) of females after mating to males that lacked seminal proteins (at 20 and 180 min, post-mating respectively). The third row shows octopamine staining of uteri (and seminal receptacle also, in the left image) of females 24hr after mating to wild-type males. The bottom row shows common oviducts of females after mating to wild-type males. The image on the left is stained for the FMRFamide dromyosuppressin, at 90’post-mating; the image on the right is stained for serotonin, at 180 min post-mating. Graphics by Zohar Nir-Amitin.