EMBRYONIC ORIGINS AND ASSEMBLY OF BLOOD-VESSELS
EMBRYONIC ORIGINS AND ASSEMBLY OF BLOOD-VESSELS
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DOI：
10.1164/ajrccm/140.4.1097
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发表时间：
1989-10-01
期刊：
影响因子：
--
通讯作者：
NODEN, DM
中科院分区：
文献类型：
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作者：
NODEN, DM
胚胎血管以两种方式发育：血管生成，即通过现有血管的萌芽、分支和延长而生长，以及原位形成与延长的血管结合的内皮小泡。假设前者更为普遍，后者仅限于在内胚层-中胚层界面附近形成的血管。这些过程中的每一个在特定血管形成中的相对贡献以及这些胚胎内皮细胞群体的前体(血管母细胞)的起源都是未知的。
Embryonic blood vessels develop in two ways: angiogenesis, which Is growth by budding, branching, and elongation of existing vessels, and in situ formation of endothelial vesicles that coalesce with elongating vessels. It is assumed that the former Is more prevelent, with the latter restricted to vessels that form near the endoderm: mesoderm interface. Neither the relative contributions of each of these processes In the formation of specific blood vessels nor the origins of precursors (angioblasts) of these Intraembryonlc endothelial populations are known.