R1ρ relaxation outside of the fast-exchange limit
R1ρ relaxation outside of the fast-exchange limit
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DOI：
10.1006/jmre.2001.2466
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发表时间：
2002-01-01
影响因子：
2.2
通讯作者：
Palmer, AG
中科院分区：
文献类型：
--
作者：
Trott, O;Palmer, AG
核磁共振波谱中的化学交换效应能够在溶液中的平衡状态下表征动力学过程。从 Bloch-McConnell 方程开始，推导了旋转坐标系中自旋弛豫速率常数 R-1rho 的新表达式，用于具有不同磁性环境和拉莫尔频率的两个位点之间的化学交换。如果自旋弛豫衰减由单一指数阻尼常数主导，并且适用于比现有理论描述更广泛的条件，则结果是准确的。当交换速度不快且位点群体不平等时，R-1rho 的新表达式在分析实验数据时特别有用。 (C) 2002 年爱思唯尔科学。
Chemical-exchange effects in NMR spectroscopy enable kinetic processes to be characterized at equilibrium in solution. Beginning with the Bloch-McConnell equations, new expressions are derived for the spin relaxation rate constant in the rotating frame, R-1rho for chemical exchange between two sites that have distinct magnetic environments and Larmor frequencies. The results are accurate provided that the spin relaxation decay is dominated by a single exponential damping constant and are applicable to a wider range of conditions than existing theoretical descriptions. The new expressions for R-1rho will be particularly useful in analyzing experimental data when exchange is not fast and site populations are unequal. (C) 2002 Elsevier Science.