Shock wave induced damage in kidney tissue
Shock wave induced damage in kidney tissue
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DOI：
10.1016/j.commatsci.2004.09.005
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发表时间：
2005-03
影响因子：
3.3
通讯作者：
K. Weinberg;M. Ortiz
中科院分区：
文献类型：
--
作者：
K. Weinberg;M. Ortiz
在一个常见的医疗程序称为冲击波碎石术超声波产生和集中在肾结石。这些冲击波被认为会使结石破碎，但也会导致肾组织损伤。为了预测和估计这种损害，我们在这里开发一个力学模型的软组织暴露的冲击波的反应。材料模型将剪切诱导有限塑性与诱导的不可逆体积膨胀相结合，例如，通过空化气泡。包括微惯性和速率敏感性等动态效应。时间离散的多孔粘塑性本构更新描述在一个完全变分的方式。有限元分析定位在人体肾脏的损伤，在良好的协议，临床和实验研究。
In a common medical procedure known as shock-wave lithotripsy hypersonic waves are generated and focused at the kidney stone. These shock waves are thought to fragment the stone but also lead to injuries of the kidney tissue. To predict and estimate this damage we develop here a mechanical model for the response of soft tissue to the exposure of shock waves. The material model combines shear induced finite plasticity with irreversible volumetric expansion as induced, e.g., by cavitating bubbles. Dynamic effects like micro-inertia and rate sensitivity are included. The time-discretized porous-viscoplastic constitutive updates are described in a fully variational manner. A finite element analysis localizes the damage in the human kidney in good agreement to clinical and experimental studies.