Survival of Helicobacter pylori in gastric acidic territory.
Survival of Helicobacter pylori in gastric acidic territory.
复制标题
DOI:
10.1111/hel.12386
复制
发表时间:
2017-08
期刊:
影响因子:
4.4
通讯作者:
Yamaoka Y
中科院分区:
文献类型:
--
作者:
Ansari S;Yamaoka Y
Helicobacter pylori is well adapted to colonize the epithelial surface of the human gastric mucosa and can cause persistent infections. Its pathogenic effects consist of gastritis, peptic ulcers and increased risk for the development of gastric cancer. In order to infect the gastric mucosa, H. pylori has to survive in the gastric acidic pH. H. pylori has well developed mechanisms to neutralize the effects of acidic pH. The exact role of many bacterial factors as well as environmental factors still remains unsolved and how these factors involve in the acid mediated survival of bacterium is unknown yet. In this review, we have discussed and summarized the various information published in scientific literatures regarding functional and molecular aspects by which the bacterium can combat and survive the adverse effects of stomach acidic pH in order to establish the persistent infections.
登录
查看更多内容
影响因子:
6.7
作者:
Bucior I;Pielage JF;Engel JN
通讯作者:
Engel JN
影响因子:
3.1
作者:
EATON, KA;BROOKS, CL;KRAKOWKA, S
通讯作者:
KRAKOWKA, S
影响因子:
4.8
作者:
Chedin, Frederic;Handa, Naofumi;Kowalczykowski, Stephen C.
通讯作者:
Kowalczykowski, Stephen C.
影响因子:
3.6
作者:
Delany, I;Spohn, G;Scarlato, V
通讯作者:
Scarlato, V
影响因子:
4.8
作者:
Chivers, PT;Sauer, RT
通讯作者:
Sauer, RT