Avaliação da qualidade de vida em pacientes com câncer de pulmão através da aplicação do questionário Medical Outcomes Study 36-item Short-Form Health Survey
Avaliação da qualidade de vida em pacientes com câncer de pulmão através da aplicação do questionário Medical Outcomes Study 36-item Short-Form Health Survey
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医疗结果研究 36 项简短健康调查
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
Ilka Lopes Santoro
中科院分区：
文献类型：
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作者：
J. Franceschini;Alecssandra Aparecida dos Santos;I. E. Mouallem;S. Jamnik;C. Uehara;Ana Luíza Godoy Fernandes;Ilka Lopes Santoro
目的：评估肺癌患者的生活质量，并与非癌症个体进行比较。方法：在圣保罗医院肺癌门诊接受治疗的57名肺癌患者和从Extra佩尼亚锻炼组招募的57名对照组患者接受了医学结局研究36项简明健康调查表（SF-36）。使用Mann-Whitney检验逐领域比较各组。第一个logistic回归模型调整了男性性别、非手术治疗、Karnofsky体能状态和吸烟，这些因素被纳入作为预测因素。第二个模型针对每个SF-36领域进行了调整，以确定IIIB或IV期患者比例的增加。研究结果：肺癌组和对照组SF-36各维度的平均得分分别为：躯体健康问题导致的角色限制（29.39 ± 36.94）分和（82.89 ± 28.80）分，情绪问题导致的角色限制（42.78 ± 44.78）分和（86.55 ± 28.77）分;躯体功能56.49 ± 28.39和89.00 ± 13.80，活力61.61 ± 23.82和79.12 ± 17.68，躯体疼痛62.72 ± 28.72和81.54 ± 19.07，一般健康62.51 ± 25.57和84.47 ± 13.47，运动功能61.61 ± 23.82和81.54 ± 19.07，运动功能62.51 ± 25.57和84.47 ± 13.47。情感幸福感分别为68.28 ± 23.46和82.63 ± 17.44，社会功能分别为72.87 ± 29.20和91.67 ± 17.44。逻辑回归模型显示，由于身体健康问题，身体功能和情绪健康的角色限制是IIIB和IV期的预测因子。结论：与对照组相比，肺癌患者的生活质量较差，特别是在身体方面。
OBJECTIVE: To assess the quality of life of patients with lung cancer and to compare it with that of individuals without cancer. METHODS: The Medical Outcomes Study 36-item Short-Form Health Survey (SF-36) was administered to 57 patients diagnosed with lung cancer, treated at the Lung Cancer Outpatient Clinic of the Hospital Sao Paulo, and to a control group of 57 individuals recruited from the Extra Penha workout group. The Mann-Whitney test was used to compare the groups, domain by domain. The first model of logistic regression was adjusted for male gender, nonsurgical treatment, Karnofsky performance status and smoking, which were included as predictors. The second model was adjusted for each SF-36 domain in order to identify increases in the proportions of patients in stage IIIB or IV. RESULTS: The lung cancer group and the control group presented the following mean scores, respectively, for the SF-36 domains: role limitations due to physical health problems, 29.39 ± 36.94 and 82.89 ± 28.80; role limitations due to emotional problems, 42.78 ± 44.78 and 86.55 ± 28.77; physical function, 56.49 ± 28.39 and 89.00 ± 13.80; vitality, 61.61 ± 23.82 and 79.12 ± 17.68; bodily pain, 62.72 ± 28.72 and 81.54 ± 19.07; general health, 62.51 ± 25.57 and 84.47 ± 13.47; emotional well-being, 68.28 ± 23.46 and 82.63 ± 17.44; and social functioning, 72.87 ± 29.20 and 91.67 ± 17.44. The logistic regression model showed that role limitations due to physical health problems, physical function and emotional well-being were predictors of stages IIIB and IV. CONCLUSIONS: The patients with lung cancer had a poorer quality of life, especially regarding physical aspects, than did the control subjects.