Association of the FilmArray Meningitis/Encephalitis Panel With Clinical Management.
Association of the FilmArray Meningitis/Encephalitis Panel With Clinical Management.
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DOI：
10.1542/hpeds.2019-0064
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发表时间：
2019-10-01
影响因子：
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通讯作者：
Snowden, Jessica
中科院分区：
文献类型：
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作者：
Nabower, Aleisha M;Miller, Sydney;Snowden, Jessica
目的：为了确定使用的多重检测脑膜炎/脑炎面板与临床管理疑似meningitis.METHODS：一个横断面研究进行了0至18岁的儿童谁收到了腰椎穿刺在48小时内入院的感染workup。收集患者的人口统计学资料和临床表现信息、实验室检查和药物给药。主要指标为住院时间（LOS），次要指标为：抗生素使用时间、抗生素使用时间和阿昔洛韦剂量。根据36小时前发生的结局对LOS和抗生素使用时间进行分层。Logistic回归分析用于解释与主要和次要结局相关的潜在混杂因素。P <0.05的值被认为具有统计学意义。结果：脑膜炎组的使用与患者LOS的可能性较高相关，
OBJECTIVES: To determine the association of the use of the multiplex assay meningitis/encephalitis panel with clinical management of suspected meningitis.METHODS: A cross-sectional study was conducted with children 0 to 18 years of age who received a lumbar puncture within 48 hours of admission for an infectious workup. Patient demographic and presenting information, laboratory studies, and medication administration were collected. The primary measure was length of stay (LOS) with secondary measures: time on antibiotics, time to narrowing antibiotics, and acyclovir doses. LOS and antibiotic times were stratified for outcomes occurring before 36 hours. Logistic regression analysis was used to account for potential confounding factors associated with both the primary and secondary outcomes. A value of P < .05 was considered statistically significant.RESULTS: Meningitis panel use was associated with a higher likelihood of a patient LOS