Estrogen exposures and memory at midlife - A population-based study of women
Estrogen exposures and memory at midlife - A population-based study of women
复制标题
DOI：
10.1212/01.wnl.0000059413.75888.be
复制
发表时间：
2003-04-22
期刊：
影响因子：
9.9
通讯作者：
Dennerstein, L
中科院分区：
文献类型：
--
作者：
Henderson, VW;Guthrie, JR;Dennerstein, L
自然绝经后雌激素的损失被假设为损害情景记忆。参加墨尔本妇女中年健康项目的326名年龄在52至63岁之间的妇女完成了一项词汇表记忆任务。雌激素暴露量可从绝经状态、末次月经的时间、激素治疗的使用、血清雌二醇浓度和其他指标推断。记忆力在大多数曝光中没有显著变化。作者的结论是，在绝经过渡期或自然绝经后的几年里，通过单词列表学习评估的情景言语记忆没有受到实质性的影响。
Estrogen loss after natural menopause is hypothesized to impair episodic memory. A total of 326 women aged 52 to 63 years participating in the Melbourne Women's Midlife Health Project completed a word list memory task. Estrogen exposures were inferred from menopausal status, time from final menstrual period, use of hormone therapy, serum estradiol concentration, and other indices. Memory did not vary significantly with most exposures. The authors conclude that episodic verbal memory assessed by word list learning is not substantially affected during the menopausal transition or in the years immediately after natural menopause.