Gli1+ Mesenchymal Stem Cells in Bone and Teeth

Gli1+ Mesenchymal Stem Cells in Bone and Teeth
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DOI:
10.2174/1574888x17666220107102911
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发表时间:
2022
期刊:
Current Stem Cell Research & Therapy
影响因子:
--
通讯作者:
Jun Wang
Jun Wang
中科院分区:
--
文献类型:
--
作者:
Yange Wu;Xueman Zhou;Wenxiu Yuan;Jiaqi Liu;Wenke Yang;Yufan Zhu;Chengxinyue Ye;Xin Xiong;Qinlanhui Zhang;Jin Liu;Jun Wang

文献摘要

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Abstract:.Mesenchymal stem cells (MSCs) are remarkable and noteworthy. Identification of markers for MSCs enables the study of their niche in vivo. It has been identified that glioma-associated oncogene 1 positive (Gli1+) cells are mesenchymal stem cells supporting homeostasis and injury repair, especially in the skeletal system and teeth. This review outlines the role of Gli1+ cells as an MSC subpopulation in both bones and teeth, suggesting the prospects of Gli1+ cells in stem cell-based tissue engineering.