Late biochemical changes in the rat lung after hemithoracic irradiation.
Late biochemical changes in the rat lung after hemithoracic irradiation.
复制标题
半胸照射后大鼠肺的晚期生化变化。
作者：
A. Dancewicz;A. Mazanowska;G. Gerber
大鼠右半胸暴露于3kr的X射线下；暴露9个月后，在不同时间处死动物，测定各种生化参数。在早期轻微减少后，胶原蛋白在纤维化阶段增加。在纤维化过程中，DNA，…-葡萄糖醛酸酶，组织蛋白酶，组胺，血清素和脂质过氧化物。在研究的大多数时间点，发现纤溶活性降低。
The right hemithorax of rats was exposed to 3 kR of X rays; the animals were sacrificed at different times after exposure up to 9 months, and various biochemical parameters were determined. After a slight early decrease, collagen increased during the fibrotic stage. An increase during fibrosis was also seen for DNA, ..beta..-glucuronidase, cathepsin, histamine, serotonin, and lipid peroxides. Fibrinolytic activity was found to be depressed at most time points studied.