Spirituality influences health related quality of life in men with prostate cancer

Spirituality influences health related quality of life in men with prostate cancer
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DOI:
10.1002/pon.929
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发表时间:
2006-02-01
期刊:
影响因子:
3.6
通讯作者:
Litwin, MS
Litwin, MS
中科院分区:
医学2区
文献类型:
--
作者:
Krupski, TL;Kwan, L;Litwin, MS

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灵性与生命的生理、心理和人际方面是相互依存的。尽管人们对乳腺癌幸存者的精神状态进行了研究,但对前列腺癌患者的研究却很少。我们试图确定早期前列腺癌男性较低的精神状态是否与较差的总体健康相关生活质量(HRQOL)、疾病特异性HRQOL或社会心理健康相关。222名研究对象来自一个国家资助的项目,该项目为贫困男性提供免费的前列腺癌治疗。经过验证的仪器捕获了灵性、一般和疾病特异性HRQOL、焦虑、症状困扰和情绪健康。我们发现精神状态和评估结果之间存在一致的关系。在控制协变量后,低灵性与较差的身心健康、性功能和更多的尿障碍显著相关。所有被研究的社会心理变量都反映出灵性低下的男性适应能力较差。由于前列腺癌存活的可能性很高,针对精神的干预可能会影响许多男性的身体和心理健康。版权所有(c) 2005 John Wiley & Sons, Ltd。
Spirituality is interdependent with the biological, psychological, and interpersonal aspects of life. Although spirituality has been studied in breast cancer survivors, little work has been done in men with prostate cancer. We Sought to determine whether lower spirituality in men with early stage prostate cancer is associated with worse general health-related quality of life (HRQOL), disease-specific HRQOL, or psychosocial health. Two hundred and twenty-two subjects were drawn from a state-funded program providing free prostate cancer treatment to indigent men. Validated instruments captured spirituality, general and disease-specific HRQOL, anxiety, symptom distress, and emotional well-being. We found a consistent relationship between spirituality and the outcomes assessed. Low spirituality was associated with significantly worse physical and mental health, sexual function and more urinary bother after controlling for covariates. All of the psychosocial variables studied reflected worse adjustment in the men with low spirituality. Because the likelihood of prostate cancer suvivorship is high, interventions targeting spirituality could impact the physical and psychosocial health of many men. Copyright (c) 2005 John Wiley & Sons, Ltd.