High-resolution brain SPECT imaging in ADHD.
High-resolution brain SPECT imaging in ADHD.
复制标题
DOI：
10.1023/a:1026201218296
复制
发表时间：
1997-06-01
期刊：
影响因子：
--
通讯作者：
Carmichael, B D
中科院分区：
文献类型：
--
作者：
Amen, D G;Carmichael, B D
使用高分辨率脑部 SPECT 成像对患有 ADHD 的儿童和青少年进行评估，以确定报告的 PET 和 QEEG 结果之间是否存在相似性。根据 DSM-III-R 和康纳斯评定量表标准对 54 名 ADHD 儿童和青少年进行了评估。还使用 SPECT 对非 ADHD 对照组进行了研究。每组进行了两项大脑 SPECT 研究，一项是静息研究，一项是在参与者进行集中注意力任务时进行的智力压力研究。 65% 的注意力缺陷多动症组显示智力压力导致前额叶皮层灌注减少，而对照组只有 5%。这些结果与 PET 和 QEEG 结果一致。在没有表现出灌注减少的多动症组中，三分之二的人在休息时前额皮质的活动明显减少。
Children and adolescents with ADHD were evaluated with high-resolution brain SPECT imaging to determine if there were similarities between reported PET and QEEG findings. Fifty-four children and adolescents with ADHD by DSM-III-R and Conners Rating Scale criteria were evaluated. A non-ADHD control group was also studied with SPECT. Two brain SPECT studies were done on each group, a resting study and an intellectual stress study done while participants were doing a concentration task. Sixty-fiver percent of the ADHD group revealed decreased perfusion in the prefrontal cortex with intellectual stress, compared to only 5% of the control group. These are findings consistent with PET and QEEG findings. Of the ADHD group who did not show decreased perfusion, two-thirds had markedly decreased activity in the prefrontal cortices at rest.