Frontal alpha EEG asymmetry before and after behavioral activation treatment for depression.
Frontal alpha EEG asymmetry before and after behavioral activation treatment for depression.
复制标题
DOI：
10.1016/j.biopsycho.2014.03.003
复制
发表时间：
2014-05
影响因子：
2.6
通讯作者：
Cacioppo J
中科院分区：
文献类型：
--
作者：
Gollan JK;Hoxha D;Chihade D;Pflieger ME;Rosebrock L;Cacioppo J
中额和中外侧（F3/F4和F7/F8）EEG不对称与动机和情感有关。我们检查了抑郁症和健康参与者在行为激活治疗抑郁症前后的α EEG不对称性;检查了α EEG不对称性与动机系统和情感之间的关联;并评估了α EEG不对称性在预测缓解中的效用。抑郁（n = 37）和健康的参与者（n = 35）进行了评估，治疗前后使用临床访谈，任务来测量基线脑电图，行为激活和抑制，回避和影响的问卷调查。治疗前抑郁症患者的α脑电不对称性显著高于健康受试者，与负性情感和行为抑制呈正相关，与较低的行为激活敏感性呈负相关。在抑郁症患者中，阿尔法脑电不对称性的增加与行为抑制和消极情绪的增加显著相关，并且与临床缓解无关。
Mid-frontal and mid-lateral (F3/F4 and F7/F8) EEG asymmetry has been associated with motivation and affect. We examined alpha EEG asymmetry in depressed and healthy participants before and after Behavioral Activation treatment for depression; examined the association between alpha EEG asymmetry and motivational systems and affect; and evaluated the utility of alpha EEG asymmetry in predicting remission. Depressed (n = 37) and healthy participants (n = 35) were assessed before and after treatment using a clinical interview, a task to measure baseline EEG, and questionnaires of behavioral activation and inhibition, avoidance, and affect. Alpha EEG asymmetry was significantly higher in depressed than healthy participants at pre-treatment, positively correlated with negative affect and behavioral inhibition, and inversely correlated with lower behavioral activation sensitivity. Heightened alpha EEG asymmetry in depressed participants was significantly associated with increased behavioral inhibition and negative emotion and was independent of clinical remission.