Relationship between preoperative hypometabolism and surgical outcome in neocortical epilepsy surgery

Relationship between preoperative hypometabolism and surgical outcome in neocortical epilepsy surgery
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DOI：
10.1111/j.1528-1167.2012.03547.x
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发表时间：
2012-08
期刊：
Epilepsia
影响因子：
5.6
通讯作者：
Chong H. Wong;A. Bleasel;L. Wen;S. Eberl;K. Byth;M. Fulham;E. Somerville;A. Mohamed
Chong H. Wong;A. Bleasel;L. Wen;S. Eberl;K. Byth;M. Fulham;E. Somerville;A. Mohamed
中科院分区：
医学1区
文献类型：
--
作者：
Chong H. Wong;A. Bleasel;L. Wen;S. Eberl;K. Byth;M. Fulham;E. Somerville;A. Mohamed

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目的：氟-18-氟脱氧葡萄糖-正电子发射断层扫描（FDG-PET）低代谢已用于定位致痫区。然而，远离发作病灶的葡萄糖代谢低下很常见，许多研究尚未考虑其与手术结局的关系。我们在一个大型新皮质癫痫患者队列中研究了手术结果与FDG-PET低代谢地形图之间的关系。
Purpose: Fluorine‐18‐fluorodeoxyglucose–positron emission tomography (FDG‐PET) hypometabolism has been used to localize the epileptogenic zone. However, glucose hypometabolism remote to the ictal focus is common and its relationship to surgical outcome has not been considered in many studies. We investigated the relationship between surgical outcome and FDG‐PET hypometabolism topography in a large cohort of patients with neocortical epilepsy.