Air Pollution-Induced Autonomic Modulation.

Air Pollution-Induced Autonomic Modulation.
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DOI:
10.1152/physiol.00017.2020
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发表时间:
2020-11
期刊:
影响因子:
8.4
通讯作者:
T. Taylor-Clark
T. Taylor-Clark
中科院分区:
医学1区
文献类型:
--
作者:
T. Taylor-Clark

文献摘要

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空气污染物对全世界的健康构成严重危害,造成呼吸系统和心血管疾病的发病率和死亡率。污染物会扰乱自主神经系统,而自主神经系统的功能对心肺内环境的稳定至关重要。最近的研究表明,污染物可以刺激心肺系统内的防御性感觉神经,从而提供了一个可能的机制,污染物引起的植物神经功能障碍。更好地了解所涉机制可能会改善与污染有关的疾病的管理和治疗。
Air pollutants pose a serious worldwide health hazard, causing respiratory and cardiovascular morbidity and mortality. Pollutants perturb the autonomic nervous system, whose function is critical to cardiopulmonary homeostasis. Recent studies suggest that pollutants can stimulate defensive sensory nerves within the cardiopulmonary system, thus providing a possible mechanism for pollutant-induced autonomic dysfunction. A better understanding of the mechanisms involved would likely improve the management and treatment of pollution-related disease.