[Incidence of cerebral palsy in Himeji over a 25-year period].

[Incidence of cerebral palsy in Himeji over a 25-year period].
复制标题

[姬路市 25 年脑瘫发病率]。

DOI:
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发表时间:
2016
期刊:
No to hattatsu = Brain and development
影响因子:
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通讯作者:
H. Miyata
H. Miyata
中科院分区:
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文献类型:
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作者:
K. Koterazawa;Yuka Okada;H. Miyata

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目的 调查日本兵库县姬路1983年至2007年脑性瘫痪病例的流行病学和临床趋势。 方法 对所有诊断为脑瘫的儿童进行了回顾性图表审查,并在作者的诊所进行了25年目标期内的并发症评估。分析并比较了5个5年区组(I:1983-1987,II:1988-1992,III:1993-1997,IV:1998-2002,V:2003-2007)中收集的数据。 结果 脑瘫的发病率每1000活产增加,直到块IV(I:1.4,II:2.0,III:2.2,IV:2.9),然后下降到2.0块V。脑瘫的最常见的原因是脑室周围白质软化症,这是常见的早产。双胞胎和三胞胎的频率是最高的第四块,导致脑瘫的发病率在这个块的升高。在并发症严重程度方面,轻度病例在研究期间增加,而重度病例的百分比仍然很高,因此导致阻滞V中严重程度的两极化分布。 结论 在研究期间观察到脑瘫的特征发生变化,最有可能是围产期最新进展的函数。
OBJECTIVE To investigate epidemiological and clinical trends of cases of cerebral palsy between 1983 and 2007 in Himeji, Hyogo, Japan. METHODS A retrospective chart review of all children diagnosed with cerebral palsy and evaluated for complications at the authors' clinic in the targeted 25-year period was conducted. Collected data were analyzed and compared across five 5-year blocks (I : 1983-1987, II : 1988-1992, III : 1993-1997, IV : 1998-2002, V : 2003-2007). RESULTS The incidence of cerebral palsy per 1000 live births increased until block IV (I : 1.4, II : 2.0, III : 2.2, IV : 2.9) and then dropped to 2.0 in block V. The most frequent cause of cerebral palsy was periventricular leukomalacia, which was common in preterm births. The frequencies of twins and triplets were highest in block IV, contributing to the elevated incidence of cerebral palsy in this block. In terms of complication severity, mild cases increased during the study period while the percentage of severe cases remained high, thus resulting in a polarized distribution of severity in block V. CONCLUSIONS The features of cerebral palsy were observed to change during the study period, most likely as functions of the recent progress in perinatal.