The macromolecular basis of the hydraulic conductivity of the arterial wall.
The macromolecular basis of the hydraulic conductivity of the arterial wall.
复制标题
动脉壁水力传导性的大分子基础。
作者：
K. Parker;C. P. Winlove
动脉壁的哪些成分决定其水力传导性的问题有两种不同的方法。首先，测量单个组分--透明质酸盐的水力特性。结果表明，单独的透明质酸不能解释动脉的高阻力，但缠绕在约束过滤器中的透明质酸具有与整个动脉测量相似的水力传导性。其次，测量了不同提取方法下的猪胸主动脉的水力特性。冷冻和高压灭菌效果不大，但碱抽提可使导水率提高三个数量级。
The question of what components of the artery wall determine its hydraulic conductivity is approached in two different ways. Firstly, the hydraulic properties of an individual component, hyaluronate, are measured. It is shown that hyaluronate alone cannot account for the high resistance of the artery but hyaluronate entangled in a restraining filter has a hydraulic conductivity similar to that measured for the whole artery. Secondly, the hydraulic properties of porcine thoracic aortae which have been subjected to various extraction procedures are measured. Freezing and autoclaving have little effect, but alkali extraction increases the hydraulic conductivity by three orders of magnitude.