A prospective study of recurrence rate and risk factors for recurrence after a first renal stone
A prospective study of recurrence rate and risk factors for recurrence after a first renal stone
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DOI：
10.1097/00005392-199907000-00007
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发表时间：
1999-07-01
影响因子：
6.6
通讯作者：
Zanetti, G
中科院分区：
文献类型：
--
作者：
Trinchieri, A;Ostini, F;Zanetti, G
目的：我们进一步调查了7至17年前首次结石发作后到我们结石诊所就诊的300名连续患者的复发率和复发风险因素。材料和方法：研究了1980年至1990年连续出现首次结石发作的患者的病历，并通过后续邮件调查问卷和电话采访进行了补充。在第一次访问时，从所有患者的血清样本和24小时尿液样本收集代谢testing.Results：共195例成功随访，其中52例（27%）经历了有症状的结石复发后，平均±标准差为7.5 +/- 5.9年。然而，36例无结石患者的超声检查显示28%的结石复发。有无复发患者的比较证实复发不受性别、结石家族史和泌尿系危险因素的影响。然而，年龄在发病时的疾病是较低的患者谁有2个或更多的结石在随访过程中比那些谁只有1个结石或没有recursion.Conclusions：结石可以复发，只要10年后，第一次发作，虽然率低于以前报道的。首次结石发作后的代谢评估需要重新评估其成本效益，因为复发似乎不能从标准的实验室检查预测。
Purpose: We investigate further the recurrence rate and risk factors for recurrence in 300 consecutive patients who presented to our stone clinic after a first stone episode 7 to 17 years ago.Materials and Methods: The medical records of the patients who presented consecutively with a first stone episode from 1980 to 1990 were studied and supplemented by a followup mail questionnaire and telephone interviews. At first visit serum samples were taken from all patients and 24-hour urine samples were collected for metabolic testing.Results: A total of 195 patients were followed successfully, of whom 52 (27%) experienced symptomatic stone recurrence after a mean plus or minus standard deviation of 7.5 +/- 5.9 years. However, ultrasound examination of 36 symptom-free patients showed recurrent stones in 28%. Comparison of patients with or without recurrence confirmed that recurrence was not influenced by sex, family history of stones and urinary risk factors. However, age at onset of the disease was lower for patients who had 2 or more stones during followup than those who had only 1 stone or no recurrence.Conclusions: Stones can recur as long as 10 years after the first episode, although the rate is lower than previously reported. The metabolic evaluation after a first stone episode needs to be reappraised in terms of its cost-effectiveness, since recurrences do not seem to be predictable from standard laboratory tests.