A novel design strategy for nanoparticles on nanopatterns: interferometric lithographic patterning of Mms6 biotemplated magnetic nanoparticles.
A novel design strategy for nanoparticles on nanopatterns: interferometric lithographic patterning of Mms6 biotemplated magnetic nanoparticles.
复制标题
纳米颗粒上的纳米颗粒的新型设计策略：MMS6生物塑造磁性纳米颗粒的干涉光刻图案。
DOI：
10.1039/c5tc03895b
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发表时间：
2016-05-14
期刊：
影响因子：
--
通讯作者：
Staniland SS
中科院分区：
文献类型：
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作者：
Bird SM;El-Zubir O;Rawlings AE;Leggett GJ;Staniland SS
自上而下的表面图案化技术、干涉光刻技术与使用 Mms6 的自下而上的磁铁矿纳米粒子生物矿化相结合，形成磁性纳米级阵列。纳米技术需要合成针对特定应用量身定制的高精度功能材料。位模式媒体就是这样的一个例子。这些高密度磁性数据存储材料需要特定且均匀的磁性纳米颗粒 (MNP) 在精确的纳米级阵列中在大面积（cm2 范围）上形成图案。然而，此类材料在纳米技术应用中的实现取决于精确且环保的可重复制造方法，以实现经济有效的规模化生产。一种潜在理想的生物制造方法是生物矿化。这是生物体内无机矿物质的形成，已知在环境条件下进行时可以在纳米尺度上受到高度控制。趋磁细菌磁螺菌 AMB-1 使用一套专用的生物矿化蛋白来控制细胞内磁铁矿 MNP 的形成。其中一种蛋白质 Mms6 已被证明可以在体外控制磁铁矿 MNP 的形成。我们之前曾在微接触印刷 (μCP) 图案化自组装单层 (SAM) 表面上使用 Mms6 来控制微型阵列中 MNP 的形成和位置，从而提供了一条仿生绿色制造路线。然而，μCP 无法可靠地产生纳米级尺寸的图案，而且大多数替代纳米制造技术速度缓慢且昂贵。干涉光刻（IL）利用激光的干涉，通过在环境条件下实施的简单过程在大面积上产生纳米结构。在这里，我们将自下而上的生物介导方法与自上而下的 IL 方法相结合，产生周期为 357 nm 的均匀磁铁矿 MNP (86 ± 21 nm) 阵列。这显示了一种潜在的革命性策略，可以在对环境影响较小的过程中生产具有纳米级精度的磁性阵列，并且可以轻松扩展该策略，以促进用于技术应用的纳米图案表面材料的大规模生产。
Top-down surface patterning technique, interferometric lithography, is combined with bottom-up magnetite nanoparticle biomineralisation using Mms6 to form magnetic nanoscale arrays. Nanotechnology demands the synthesis of highly precise, functional materials, tailored for specific applications. One such example is bit patterned media. These high-density magnetic data-storage materials require specific and uniform magnetic nanoparticles (MNPs) to be patterned over large areas (cm2 range) in exact nanoscale arrays. However, the realisation of such materials for nanotechnology applications depends upon reproducible fabrication methods that are both precise and environmentally-friendly, for cost-effective scale-up. A potentially ideal biological fabrication methodology is biomineralisation. This is the formation of inorganic minerals within organisms, and is known to be highly controlled down to the nanoscale whilst being carried out under ambient conditions. The magnetotactic bacterium Magnetospirillum magneticum AMB-1 uses a suite of dedicated biomineralisation proteins to control the formation of magnetite MNPs within their cell. One of these proteins, Mms6, has been shown to control formation of magnetite MNPs in vitro. We have previously used Mms6 on micro-contact printed (μCP) patterned self-assembled monolayer (SAM) surfaces to control the formation and location of MNPs in microscale arrays, offering a bioinspired and green-route to fabrication. However, μCP cannot produce patterns reliably with nanoscale dimensions, and most alternative nanofabrication techniques are slow and expensive. Interferometric lithography (IL) uses the interference of laser light to produce nanostructures over large areas via a simple process implemented under ambient conditions. Here we combine the bottom-up biomediated approach with a top down IL methodology to produce arrays of uniform magnetite MNPs (86 ± 21 nm) with a period of 357 nm. This shows a potentially revolutionary strategy for the production of magnetic arrays with nanoscale precision in a process with low environmental impact, which could be scaled readily to facilitate large-scale production of nanopatterned surface materials for technological applications.