Preoperative anemia and outcomes in patients undergoing surgery for inflammatory bowel disease
Preoperative anemia and outcomes in patients undergoing surgery for inflammatory bowel disease
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DOI：
10.1016/j.amjsurg.2017.02.016
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发表时间：
2018-01-01
影响因子：
3
通讯作者：
Nfonsam, V. N.
中科院分区：
文献类型：
--
作者：
Michailidou, M.;Nfonsam, V. N.
背景：贫血是炎症性肠病(IBD)患者最常见的肠外表现，并与疾病的严重程度有关。该研究的目的是评估贫血对IBD患者术后预后的影响。方法：我们回顾了8年来NSQIP数据库中的IBD患者。患者根据贫血的存在情况进行分组。评估贫血对术后发病率、死亡率和住院时间的影响。结果：共有15,761名患者符合我们的标准。半数患者出现贫血症状。贫血患者更有可能有类固醇使用史，出现败血症，需要紧急手术。在多变量分析中，贫血是总体发病率、严重发病率和住院时间增加的显著预测因素。结论：与同龄人相比，IBD贫血患者更容易出现败血症，需要紧急手术。此外，贫血是腹部手术后总体并发症、严重发病率和住院时间延长的独立预测因子。由爱思唯尔公司出版。
Background: Anemia is the most common extraintestinal manifestation in patients with inflammatory bowel disease (IBD), and has been linked to severity of the disease. The aim of the study was to assess the impact of anemia on postoperative outcomes in patients with IBD.Methods: We retrospectively reviewed patients with IBD from the NSQIP database over an 8-year period. Patients were grouped based on the presence of anemia. The impact of anemia on postoperative morbidity, mortality and length of stay was assessed.Results: A total of 15,761 patients met our criteria. Half of the patients were anemic upon presentation. Anemic patients were more likely to have a history of steroid use, present with sepsis and require an emergency operation. In multivariate analysis, anemia was a significant predictor of overall morbidity, serious morbidity and increased length of stay.Conclusions: Anemic patients with IBD present more often with sepsis and require emergency surgery compared to their peers. In addition, anemia serves as an independent predictor of overall complications, serious morbidity and increased length of stay following abdominal operations. Published by Elsevier Inc.