Growth Control: A Saga of Cell Walls, ROS, and Peptide Receptors
Growth Control: A Saga of Cell Walls, ROS, and Peptide Receptors
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DOI：
10.1105/tpc.114.125518
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发表时间：
2014-05
期刊：
影响因子：
11.6
通讯作者：
Sebastian Wolf;H. Höfte
中科院分区：
文献类型：
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作者：
Sebastian Wolf;H. Höfte
尽管对内源性和环境生长控制信号及其信号网络的了解越来越详细，但对这些网络如何与细胞扩增机制整合知之甚少。CrRLK 1 L家族的成员在各种发育和环境背景下控制细胞壁特性和细胞扩增。最近的两份报告为这些RLK的作用模式提供了令人兴奋的新见解。一项研究表明，一个家庭成员，FERONIA（FER），需要在雌配子体中产生羟基自由基，这会导致花粉管破裂和精子在受精过程中释放。另一项研究表明，FER是一种信号肽（快速碱化因子1 [RALF 1]）的受体，可能通过抑制质膜H+-ATP酶活性触发细胞壁碱化和生长停滞。RALF 1是一个大的基因家族，具有广泛的表达模式。因此，其他CrRLK 1 L家族成员也可能是RALF样肽的受体。这些发现对我们理解生长过程中细胞壁完整性的控制具有重要意义，并提出了新的有趣的问题。
Despite an increasingly detailed understanding of endogenous and environmental growth-controlling signals and their signaling networks, little is known on how these networks are integrated with the cell expansion machinery. Members of the CrRLK1L family control cell wall properties and cell expansion in a variety of developmental and environmental contexts. Two recent reports provide exciting new insights into the mode of action of these RLKs. One study shows that one family member, FERONIA (FER), is required for the production of hydroxyl radicals in the female gametophyte, which causes pollen tube rupture and sperm cell release during fertilization. Another study shows that FER is a receptor for a signaling peptide (Rapid Alkalinization Factor 1 [RALF1]) that triggers cell wall alkalinization and growth arrest, possibly through the inhibition of plasma membrane H+-ATPase activity. RALF1 belongs to a large gene family, with a wide range of expression patterns. Other CrRLK1L family members therefore may also be receptors for RALF-like peptides. These findings have important implications for our understanding of the control of cell wall integrity during growth and raise new intriguing questions.