Sentinel Lymph Node Intraoperative Imprint Cytology in Patients with Breast Cancer-Costly or Cost Effective?
Sentinel Lymph Node Intraoperative Imprint Cytology in Patients with Breast Cancer-Costly or Cost Effective?
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DOI：
10.1245/s10434-010-1130-0
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发表时间：
2010-11-01
影响因子：
3.7
通讯作者：
Levine, Edward A.
中科院分区：
文献类型：
--
作者：
Kaminski, Jan P.;Case, Doug;Levine, Edward A.
背景前哨淋巴结（SLN）活检现在是乳腺癌患者的标准治疗。术中印记细胞学（IIC）向外科医生提供结果，当转移呈阳性时，可能会导致在相同麻醉下进行淋巴结切除术。因此，一个积极的IIC可以节省病人的第二次手术和与之相关的费用it.The本研究的目的是评估TIC在乳腺癌patients.Materials和Methods的成本效益。本研究评估了2008年7月至2009年5月期间接受SLN活检的98例患者。根据IIC和永久切片的结果将患者分为3组：（1）真阴性（TN）IIC，（2）真阳性（TP）IIC和（3）假阴性（FN）IIC。回顾性提取每例患者的总费用，非参数检验评估三组之间费用的差异。每例患者的总费用中位数分别为：（1）14，764.62美元，（2）19，025.89美元，（3）29，750.64美元（P
Background. Sentinel lymph node (SLN) biopsy is now standard of care for breast cancer patients. lntraoperative imprint cytology (IIC) provides results to the surgeon, which may lead to a lymphadenectomy under the same anesthetic when it is positive for metastases. Thus, a positive IIC can spare the patient a second operation and the charges associated with it. The aim of this study is to assess the cost effectiveness of TIC in breast cancer patients.Materials and Methods. This study evaluated 98 patients who underwent a SLN biopsy between July 2008 and May 2009. The patients were divided into 1 of 3 groups based on the results of IIC and permanent sections: (1) true-negative (TN) IIC, (2) true-positive (TP) IIC, and (3) false-negative (FN) IIC. Total charges for each patient were extracted retrospectively, and nonparametric tests assessed differences in the charges between the three groups.Results. The median total charges per patient for each population were the following: (1) $14,764.62, (2) $19,025.89, and (3) $29,750.64 (P